UW-Madison facility starts manufacturing COVID-19 treatment drug | Higher education
![Production bioreactor](https://bloximages.chicago2.vip.townnews.com/madison.com/content/tncms/assets/v3/editorial/e/96/e96120ba-a626-52b8-9048-4c2b484b6651/5f5975a8c5525.image.jpg?resize=1200%2C900)
Waisman Biomanufacturing staff member Rachel Mosher adjusts the controls on a production bioreactor like the one in which antibodies for a drug developed to treat COVID–19 will be produced.
A lab at UW-Madison’s Waisman Center started manufacturing a new drug to treat COVID-19 patients, the university announced Wednesday.
Waisman Biomanufacturing is working with GigaGen, a California-based biotechnology company, on a drug that uses an approach similar to treating COVID-19 patients with convalescent plasma, or blood products from people recovering from an infection.
The drug, called GIGA-2050, is “one of the most exciting manufacturing challenges we have encountered,” Waisman Biomanufacturing director Carl Ross said in a university announcement.
Waisman Biomanufacturing staff member Dave Richards purifies antibodies for a drug developed to treat and prevent COVID–19 developed by the biotech company GigaGen.
GigaGen screened blood donated by people recovering from COVID-19 and found large variation in the amount of antibodies among patients. Antibodies are proteins created by the immune system to detect and fight off a virus.
Manufacturing of the drug relies upon a technique that involves genetically engineering cells to produce many thousands of different antibodies that bind to the virus.
Waisman scientists will analyze and purify the results to manufacture into a drug product for GigaGen. The company creates a variety of antibody drugs for infectious diseases and cancers.
GigaGen reports that lab tests show GIGA-2050 has been more protective against the virus than plasma. The company is planning multiple phases of testing, which will be produced by Waisman Biomanufacturing and a biotech company in Florida.